cGMP signals in smooth muscle cells and cardiac myocytes

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cGMP signals in smooth muscle cells and cardiac myocytes

Background cGMP plays an important role in the cardiovascular system and is involved in smooth muscle relaxation and inhibition of platelet aggregation. cGMP concentrations inside cells are determined by an interplay of cGMP synthesis through natriuretic peptide or NO receptor guanylyl cyclases on the one hand and cGMP-degrading phosphodiesterases on the other hand. Phosphodiesterase 5 has been...

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ژورنال

عنوان ژورنال: BMC Pharmacology

سال: 2011

ISSN: 1471-2210

DOI: 10.1186/1471-2210-11-s1-p40